When to do amniocentesis for cystic fibrosis?

Amniocentesis for cystic fibrosis is typically performed during the second trimester, usually between 15 and 20 weeks of gestation. It is recommended for pregnant women who are carriers of the cystic fibrosis gene or when there is a family history of the condition. The procedure involves extracting amniotic fluid to test for mutations in the CFTR gene, allowing for early detection of cystic fibrosis in the fetus. Counseling and informed consent are essential before proceeding with the test.