TPA (tissue plasminogen activator) infusions should be stopped if there are signs of bleeding, such as sudden headache, changes in consciousness, or any signs of intracranial hemorrhage. Additionally, if the patient develops severe hypotension or anaphylactic reactions, the infusion should be discontinued immediately. Other indications include reaching the maximum recommended dose or if there are contraindications that arise during treatment. Always consult clinical guidelines and protocols for specific threshold values or symptoms.
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