You can pet the dog where the topical isn't applied. They say 48-72 hours before bathing after application depending on which flea and tick stuff you usem. We use the one in the blue applictor package (frontline I think???) when I read the instructions it didn't warn about keeping your hands off or call disease control if you get it on ya. I would just not pet directly on the applied spots until it looks to be dry. (few hours). Belly rubs are just as good :)
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