The cornified layer, also known as the stratum corneum, is the outermost layer of the epidermis in the skin. Its primary function is to provide a protective barrier against environmental factors such as pathogens, chemicals, and physical abrasions. This layer consists of dead, flattened keratinocytes that are rich in keratin, which helps to prevent water loss and maintain hydration in the underlying layers of skin. Additionally, it plays a crucial role in regulating permeability and contributing to overall skin integrity.
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