Is it normal to have a period while on lupron depot treatments for several months?

It is not uncommon to experience menstrual bleeding while on Lupron Depot, especially during the initial months of treatment. Lupron Depot is designed to suppress estrogen production, which may lead to lighter periods or amenorrhea (absence of periods) over time. However, individual responses can vary, and any persistent or concerning bleeding should be discussed with a healthcare provider for proper evaluation.