Can you take excedrin and soma?

Possibly.

Excedrin (Extra Strength and Migraine) contains three ingredients: acetaminophen (Tylenol), aspirin (an NSAID), and caffeine.

Soma (carisoprodol) is a medication used as a muscle relaxant. Soma also comes in a preparation where it contains carisoprodol with aspirin, or carisoprodol with aspirin and codeine.

Combining Excedrin with Soma only should be safe. However, combining Excedrin (250mg of aspirin per tablet, 500mg of aspirin per dose) with the Soma compound containing aspirin (325mg of aspirin per tablet) may mean you are getting more aspirin in a single dose than is considered safe.