Can dipenhyromine cause a false positive?

Yes, diphenhydramine can potentially cause a false positive in drug tests, particularly those screening for certain substances like amphetamines. This is due to its chemical structure and how some testing methods may misidentify it. However, confirmatory tests are typically more accurate and can differentiate between diphenhydramine and other substances. If there are concerns about drug testing results, it's advisable to inform the testing facility about any medications taken.