Was the signing of the Magna Carta the major European event that occured during the Renaissance?

if you are talking about the magna carta in 1215, then no. it was only relative to england herself really. also, it was not even signed in the renaissance period.

historical events such as reformation, counter reformation, sack of rome, constantinople falls, discovery of the "new world", first female english monarch, et cetera. there were many many major events you just need to narrow it down.