Is there a cheat in WolfQuest that will protect your pups from being attacked?

The game is made with Unity 3D, so the only "cheats" that really exist are the bugs and glitches left (however unintentionally) in the game by the developers. To answer, no; you will need to protect your pups by fighting against predators. There's no cheat to protect against them, but there is a bug. ;)

There is a bug in the game that allows you to protect your pups easily, however this only works against coyotes and bears; it will not protect against the eagle during the final mission. When a predator does appear, make a note of which pup it has targeted. When you know, go to that puppy and press 'z' to fall asleep beside it and skip to another time.

When you wake, the predator should be gone and the puppy will have been saved. It's really only necessary to do this when there are grizzly bears around, since coyotes are easily killed.