What angered the subject of the Persian Empire and caused them to rebel?

The Persian Empire comprised many people, some of whom at different times rebelled for different reasons. The Greek city-states in Asia Minor rebelled over losing independence, after being stirred up by a Greek tyrant appointed by the Persians who was in trouble with the Persian governor. There were rebellions in Central Asia, and in Egypt, usually stirred up by a local ruler trying to gain dominance and secession.