The cells involved in bone breakdown and resorption of bone are?

The cells involved in bone breakdown and resorption are primarily osteoclasts. These multinucleated cells originate from monocyte/macrophage lineage and are responsible for the degradation of bone tissue by secreting acids and enzymes that dissolve mineralized bone matrix. This process is crucial for bone remodeling and maintaining calcium homeostasis in the body. Osteoclast activity is balanced by osteoblasts, which are responsible for bone formation.