How long does hydrocodone take to start working?

For the average person:

• Onset: ≈10-30 minutes
• The peak can be about ≈30-60 minutes
• The typical half-life of hydrocodone is about 3.8-6 hours
• The effects in total can last between 3-6 hours

It all depends on you metabolism, age, and any other drugs you are taking. The metabolism can also be affected by the amount of food in your stomach, which could delay the onset.