Why does nose spray need to be stored upright?

Nose spray needs to be stored upright to ensure that the medication remains properly mixed and doesn't settle or separate within the bottle. Storing it upright helps maintain the integrity of the delivery mechanism, ensuring accurate dosing and effective application. Additionally, it prevents leakage or clogging of the nozzle, which can occur if the spray is stored on its side. Proper storage helps ensure the medication's efficacy and safety when used.