Which type of medication acts on plasminogen causing clots to disintegrate?

Fibrinolytic medications, also known as thrombolytics, act on plasminogen to facilitate the breakdown of blood clots. These drugs convert plasminogen into plasmin, an enzyme that dissolves fibrin, the protein that forms the structure of clots. Common examples include alteplase, reteplase, and tenecteplase, which are often used in emergency situations such as acute myocardial infarction or ischemic stroke.