To calculate the coupling constant of a triplet of doublets, you first identify the splitting pattern in the NMR spectrum. Each doublet arises from the interaction of a proton with its neighboring protons, leading to distinct peaks. The coupling constant (J) can be determined by measuring the distance between the peaks in Hz. For a triplet of doublets, you would typically calculate the coupling constants between the groups of protons that lead to the observed splitting, often resulting in two different J values for the two sets of doublets.
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