What happens to the other organisms in a food chain when an organism in the middle of the food chain is lost?

When an organism in the middle of a food chain is lost, it can disrupt the balance of the entire ecosystem. The organisms that rely on it for food may experience a decline in population due to the lack of available resources. Conversely, the populations of its prey may increase unchecked, leading to overgrazing or depletion of vegetation. This cascading effect can ultimately result in significant changes to the ecosystem's structure and function.