How can I properly tune and adjust the new strings on my guitar for optimal sound quality and playability?

To properly tune and adjust new strings on your guitar for optimal sound quality and playability, use a tuner to tune each string to the correct pitch. Stretch the strings gently to help them settle in, then fine-tune each string again. Adjust the bridge and nut if needed to ensure proper string height and intonation. Experiment with different string gauges and brands to find the best sound and feel for your playing style.