Will my PC run command and conquer 3 kanes wrath im using amd e-300 apu with radeon hd graphics 1.30 ghz. windows 7 64 bit?

Command & Conquer 3: Kane's Wrath has relatively modest system requirements, and your AMD E-300 APU with Radeon HD graphics should be able to run the game, albeit at lower settings. The game requires a minimum of a 2.0 GHz single-core processor or equivalent, so while your CPU is below that, it may still function in a limited capacity. Overall, you might experience reduced performance and graphics quality, but it should be playable.