Can you give your dog Excedrin?

No, Excedrin has the same active ingredient as Tylenol and is very dangerous to dogs. Dogs are exceptionally sensitive to the side effects of human pain medications (Tylenol, Excedrin, Advil, Aleve, Motrin, aspirin, acetominophen, ibuprofen, etc) and you can cause a fatal stomach ulcer with them pretty easily.

If you believe your dog would benefit from pain medication, you need to schedule an appointment with your veterinarian. There are safe and relatively cheap drugs to help control mild to moderate pain in your dog, but you can only get them with a veterinary prescription.