What is the relationship between skin and lymphnodes?

The skin and lymph nodes are both integral components of the immune system. The skin acts as a physical barrier, protecting the body from pathogens, while lymph nodes filter lymph fluid and trap foreign substances, including pathogens and cancer cells, for immune response. Additionally, immune cells within the skin can migrate to lymph nodes to activate and amplify the immune response, illustrating a dynamic interaction between these two systems in maintaining overall health.