Continuing review of an approved and ongoing protocol?

Continuing review of an approved and ongoing protocol refers to the regular evaluation of research studies by an Institutional Review Board (IRB) to ensure compliance with ethical standards and participant safety. This process typically occurs at least annually and assesses any new developments, adverse events, or changes in the study's risk-benefit ratio. It ensures that the research remains aligned with ethical guidelines and regulatory requirements throughout its duration. Additionally, any modifications to the protocol must be approved by the IRB before implementation.