A chronic bone disease characterized by the abnormal breakdown of bone followed by abnormal bone formation is known as Paget's disease of bone. This condition disrupts the normal cycle of bone renewal, leading to enlarged and weakened bones, which may result in pain, deformities, and an increased risk of fractures. The exact cause of Paget's disease is not fully understood, but it may involve genetic and environmental factors. Treatment often includes medications to manage symptoms and reduce bone turnover.
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