What is the best way to trim toenails?

Nail clippers is the best way to shorten a toenail. Nail files work as well.

If you mean to remove an ENTIRE toenail, this should not be done under any circumstances unless there is an infection beneath the nail, or any other medical problems. If this is the case, then contact a doctor. You may need surgery.

DO NOT try to remove the nail yourself. This is very dangerous, not to mention painful.

Consult a doctor, surgeon, or any other medical assistant for help with this. Best of luck.