A 12-pound stuffed turkey typically takes about 3 to 3.5 hours to cook at an oven temperature of 325°F (163°C). It's essential to use a meat thermometer to ensure the internal temperature of the turkey reaches at least 165°F (74°C) in the thickest part of the breast and the center of the stuffing. Always let the turkey rest for about 20 minutes before carving to allow the juices to redistribute.
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