Marijuana related deaths in America

You can't die from smoking too much pot, its impossible for a variety of reasons, primarily because the cannabinoid receptors reside primarily in the brain (amongst other locations in the body) and opiate receptors reside in the brain stem- this controls respiration or breathing.

Death will occur from an overdose of opiates in most cases for this reason, contrarily, marijuana does not have effects on respiration. Large amounts can be taken without serious adverse effects other than getting extremely high.