How would you say you are mad in shakespearean language?

There is no such language as "Shakespearean language". He wrote in English, and he might well have said "You are mad" as "You are mad". Antony in Julius Caesar says "You are not wood, you are not stones, but men, and being men, hearing the will of Caesar, it will inflame you, it will make you mad." Of course, sometimes (but not always by any means) Shakespeare used the old pronoun "thou" and its verb forms for the singular forms of "you". So Lady Macbeth says to the messenger "Thou art mad to say it".

Although Shakespeare often used the Word "mad" he only used it in the sense of "insane". The sense of "angry" has developed in some English dialects since and in American dialects has overtaken the older meaning. Shakespeare would have said "angry" by using the Word "angry"