Can you take Tylenol or Advil while taking Cephalexin?

If you are taking only these drugs together, they are a safe combination. Acetaminophen (or Tylenol) is in many cold and flu medications such as DayQuil and NyQuil and is a very common pain reliever/fever reducer and possibly one of the most recommended by doctors for minor pain and fever. Just make sure to drink plenty of water with any medications to ensure that your body is able to eliminate any toxins properly and to help avoid kidney or liver problems. Also, make sure to follow dosing correctly and take the lowest effective dose.