How far is Galveston TX to Destin Fl?

The distance from Galveston, TX, to Destin, FL, is approximately 450 miles (725 kilometers) when traveling by road. The journey typically takes around 6.5 to 7.5 hours, depending on traffic and route taken. If flying, the distance is about 360 miles (580 kilometers), with flight times varying based on layovers.