What is M-SPIKE in urine?

M-SPIKE in urine refers to the presence of a monoclonal protein spike detected in a urine protein electrophoresis test. It is often associated with conditions like multiple myeloma or other plasma cell dyscrasias, where abnormal plasma cells produce excess monoclonal antibodies. The presence of an M-SPIKE can help in diagnosing these conditions and monitoring the disease's progression or response to treatment.