How do you play an e in the fourth octave on flute?

To play an E in the fourth octave on the Flute, you'll need to use the proper fingering and breath support. The fingering for high E (E4) is typically played by pressing down the first three fingers of the left hand and the first two fingers of the right hand, while leaving the pinky fingers off. Additionally, ensure you have a strong and focused airstream, as this will help produce a clear and stable sound in the higher register. Adjust your embouchure slightly by tightening it to achieve the desired pitch.