While both conditions are caused by viral infections, Dengue (or Dengue Fever) could be blamed on mosquitoes, mainly the Aedes aegypti types, flu, (or Influenza), on the other hand, is the result of influenza virus infections, (types A, B, or C), and can be caught from other persons (usually from coughs and sneezes).
Since Dengue Fever is transmitted by mosquitoes, it is usually found where these mosquitoes live, - at tropical and subtropical regions. Flu could be anywhere, causing periodical widespread epidemics or pandemics, most likely at winter or spring times.
While several, common symptoms, such as fever, headache, muscle and joint pains could make both conditions very uncomfortable, they have their own, additional symptomes, and are quit different in many other ways.
Dengue hemorrhagic fever (DHF), a type of Dengue fever, for example, as the name suggests, could cause bleeding and even shock, therefore, could be considered a quite serious condition. Flu, can have serious, potentially fatal complications as well, mostly for immune compromised persons.
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