What is highest HDL levels and lowest?

High-density lipoprotein (HDL) cholesterol levels are typically considered optimal when they are above 60 mg/dL, as higher levels are associated with a reduced risk of Heart disease. Levels below 40 mg/dL for men and 50 mg/dL for women are considered low and may increase cardiovascular risk. It's important to consult with a healthcare provider for individual assessments and recommendations.