How long does it take to get from Columbia SC to Myrtle Beach SC?

The drive from Columbia, SC, to Myrtle Beach, SC, typically takes about 2 to 2.5 hours, depending on traffic and road conditions. The distance is approximately 120 miles, and the most common route is via I-20 E and US-501 N. It's advisable to check for real-time traffic updates before your trip for the most accurate travel time.