The Indian Removal Act of 1830 primarily affected several Native American groups, including the Cherokee, Creek, Seminole, Chickasaw, and Choctaw tribes. These groups faced forced relocation from their ancestral lands in the southeastern United States to designated Indian Territory west of the Mississippi River. The Act aimed to open up land for American settlers and agriculture, leading to significant cultural and social disruptions for the affected tribes. Additionally, it contributed to the broader context of American expansionism and the displacement of Indigenous peoples.
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