Ketosis develops when the body depletes its glycogen stores due to a significant reduction in carbohydrate intake, leading to lower insulin levels. In response, the liver begins to convert fatty acids into ketone bodies, which serve as an alternative energy source. This metabolic state typically occurs during prolonged fasting, strict low-carbohydrate diets, or intense exercise. As ketone levels rise in the bloodstream, the body shifts from using glucose to utilizing fat for energy.
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