Where do granulocytes come from?

Granulocytes originate from pluripotent hematopoietic stem cells in the bone marrow. These stem cells differentiate into myeloid progenitor cells, which further develop into granulocyte precursors. Through a series of maturation stages, these precursors eventually become the three main types of granulocytes: neutrophils, eosinophils, and basophils. Once fully mature, granulocytes are released into the bloodstream to perform their immune functions.