At the end of BiOShock, there are 3 alternate endings, depending on how you played the game.
If you decide to rescue all the Little Sisters, you will get an ending where you refuse the key to Rapture, and grow up on Earth to watch your daughters grow up.
If you decide to harvest at least 1 Little Sister, you take the key to the city and abuse the Little Sisters. You send an attack to the surface and Spider Splicers attack a nuclear submarine.
If you harvest all of the Little Sisters, then the same video as ending 2 is played, but Tenenbaum's voiceover is angry rather than sad.
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