What happens when you don't have any nucleotides?

Without nucleotides, the building blocks of DNA and RNA, cells cannot synthesize genetic material, which is essential for replication and protein synthesis. This would halt cell division and growth, impairing overall cellular function and leading to cell death. Additionally, without nucleotides, critical metabolic processes dependent on nucleotides, such as energy transfer (via ATP) and signaling, would be disrupted. Ultimately, the absence of nucleotides would severely compromise life at the molecular level.