Patients with Chronic Lymphocytic Leukemia (CLL) can develop large amounts of blood clots due to a combination of factors, including increased blood viscosity from elevated white blood cell counts and potential dysfunction of platelets. The disease can also lead to a hypercoagulable state, where the balance of clotting and bleeding is disrupted. Additionally, splenomegaly (enlarged spleen) in CLL can contribute to altered blood flow and stasis, further increasing the risk of thrombus formation in the spleen, liver, and lungs.
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