If the trunk of your 2001 Mercedes S430 isn't opening with the remote or the inside button, it could be due to a few issues. The trunk release mechanism might be malfunctioning, or there could be a blown fuse affecting the electric trunk release. Additionally, a dead key fob battery or a problem with the central locking system could also prevent the trunk from opening. It's advisable to check these components or consult a professional for a thorough diagnosis.
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