Cholelithiasis refers to the formation of gallstones in the gallbladder without the presence of inflammation, known as cholecystitis. These gallstones can be composed of cholesterol, bilirubin, or a mix of both and may vary in size. While many individuals with cholelithiasis may experience no symptoms, some can have episodes of biliary colic, characterized by pain in the upper abdomen. The condition can lead to complications if the stones obstruct bile flow, but it does not involve the inflammation typical of cholecystitis.
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