In 1617, many Indigenous people in North America, particularly in the region around the Plymouth Colony, died due to a combination of factors, including the outbreak of epidemics, likely brought by European settlers. These diseases, such as smallpox, had devastating effects on Native populations who had no immunity. Additionally, the disruption of their traditional ways of life and conflicts with settlers contributed to the mortality rates. The combination of these factors led to significant loss of life among Indigenous communities during that period.
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