Can you talk to a walkie talkie using a citizen band radio?

That depends on what type of handheld radio you're using. They do make handheld CB radiOS. They have both 40 channel handhelds, and single channel handhelds (some of which may actually be three channel with the purchase of additional radio crystals). The single channel handhelds typically use Channel 14 as a default.

FM radiOS, such as those used in FMRS, GMRS, Business Radio, emergency services, etc. do not use the same frequencies as CB radiOS, and cannot communicate with them.