Which term best describes a noninfected lesion formed by buildup in a hair follicle?

The term that best describes a noninfected lesion formed by a buildup in a hair follicle is "comedo." Comedones can be open (blackheads) or closed (whiteheads) and occur when dead skin cells, oils, and debris clog the follicle. They are commonly associated with acne but do not involve bacterial infection.