How antipsychotics affect neurotransmitters?

Antipsychotics primarily affect neurotransmitter systems in the brain, particularly dopamine and serotonin. They typically work by blocking dopamine D2 receptors, which helps reduce symptoms of psychosis by lowering dopamine activity. Some atypical antipsychotics also influence serotonin receptors, promoting a more balanced neurotransmitter environment that can alleviate mood symptoms and improve overall treatment efficacy. This modulation of neurotransmitters helps stabilize mood and reduce hallucinations and delusions in individuals with psychotic disorders.