What empires were destroyed by the Spanish?

The Spanish destroyed several empires during their conquests, most notably the Aztec Empire in present-day Mexico and the Inca Empire in South America. The fall of the Aztecs occurred in 1521, led by Hernán Cortés, while the Inca Empire fell in 1533 under Francisco Pizarro's command. Additionally, the Spanish engaged in the decline of various indigenous groups and smaller polities throughout the Americas, significantly altering the region's political landscape.