How many animals are killed for one cosmetic?

Researchers kill between 1 and 1,300 animals may be killed for each cosmetic ingredient tested. Here are some common tests and the numbers of animals killed for each:

1. Skin sensitization: 32 guinea pigs or 16 mice
   
2. Skin irritation/corrosion: 1-3 rabbits
   
3. Eye irritation/corrosion: 1-3 rabbits
   
4. Acute oral toxicity: 7 rats
   
5. Acute dermal toxicity: 20 rats, rabbits, or guinea pigs
   
6. Acute inhalation toxicity: 20 rats
   
7. Repeat dose (28 day) and subchronic (90 day) toxicity: 40 rats (28 day) or 80 rats (90 day)
   
8. Carcinogenicity or combined carcinogenicity/chronic toxicity: 400 mice or rats
   
9. Toxicokinetics: 4-12 rats
   
10. Reproductive/developmental screen: 675 rats
    
11. Reproductive toxicity in two generations: 2,600 rats
    
12. Developmental toxicity: 480 rabbits (100 adult females and 480 pups) or 1,300 rats (100 adult females and 1,200 pups)
    
13. Genotoxicity/mutagenicity: 12-500 mice or rats