Why take at bedtime Simvistatin?

Since the body produces most of its cholesterol while sleeping, taking statins at night makes them most effective at blocking cholesterol production throughout the night. However, certain statins like atorvastatin (Lipitor) and rosuvastatin (Crestor) stay in the body for longer than the other statins, so they can generally be taken at any time of day. Also, lovastatin (Mevacor) should be taken with food in order to be sufficiently absorbed.