Are actress Holly Marie Combs and the late Ray Combs related?

No, actress Holly Marie Combs and the late Ray Combs are not related. Holly Marie Combs is known for her roles in "Charmed" and "Picket Fences," while Ray Combs was a comedian and game show host best known for his work on "Family Feud." They share a common last name, but there is no familial connection between them.