"Twinkle, Twinkle, Little Star" is typically played in the key of C major and consists of a simple melody that follows a straightforward pattern. The primary notes are C, C, G, G, A, A, G, and then it repeats this pattern with some variations. The melody generally aligns with the lyrics, making it easy to sing along. For example, the first line corresponds to the notes C-C-G-G-A-A-G.
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